由狂牛症淺談傳染性海綿狀腦病變及庫賈氏病 | 全球疫情雷達
由江佳錡著作·2006·被引用1次—普利旺蛋白質;普利旺病;傳染性海綿狀腦病變;狂牛症;庫賈氏病;prions;priondisease;transmissiblespongiformencephalopathy;madcow ...
Prion protein is one of the well-known infectious pathogens and the only pathogen which is devoid of nucleic acid. Not like other viral and bacterial infections, prion diseases result from the conversion of normal cellular prion protein to disease-causing isoform through various ways, such as infection, heredity, mutation, or spontaneous conversion. Prion disease is also named as transmissible spongiform encephalopathy because the spongiform degeneration is noted in the brain of infected animals. The clinical manifestations include dementia, ataxia, insomnia, deviant behavior, etc. The clinical course is progressive rapidly, and death always occurs in the terminal phase of the illness. There is no effective therapy for treating prion diseases in the present medical field. Not only the pathogenic mechanisms but also the curing courses have become the serious challenges and topics ...
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庫賈氏病 2021/2/25 通報,發生國家:肯亞
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